Amazon.com Review Amazon Best Books of the Month, February 2010: From a single, abbreviated life grew a seemingly immortal line of cells that made some of the most crucial innovations in modern science possible. And from that same life, and those cells, Rebecca Skloot has fashioned in The Immortal Life of Henrietta Lacks a fascinating and moving story of medicine and family, of how life is sustained in laboratories and in memory. Henrietta Lacks was a mother of five in Baltimore, a poor African American migrant from the tobacco farms of Virginia, who died from a cruelly aggressive cancer at the age of 30 in 1951. A sample of her cancerous tissue, taken without her knowledge or consent, as was the custom then, turned out to provide one of the holy grails of mid-century biology: human cells that could survive--even thrive--in the lab. Known as HeLa cells, their stunning potency gave scientists a building block for countless breakthroughs, beginning with the cure for polio. Meanwhile, Henrietta's family continued to live in poverty and frequently poor health, and their discovery decades later of her unknowing contribution--and her cells' strange survival--left them full of pride, anger, and suspicion. For a decade, Skloot doggedly but compassionately gathered the threads of these stories, slowly gaining the trust of the family while helping them learn the truth about Henrietta, and with their aid she tells a rich and haunting story that asks the questions, Who owns our bodies? And who carries our memories? --Tom Nissley
Amazon Exclusive: Jad Abumrad Reviews The Immortal Life of Henrietta Lacks
Jad Abumrad is host and creator of the public radio hit Radiolab, now in its seventh season and reaching over a million people monthly. Radiolab combines cutting-edge production with a philosophical approach to big ideas in science and beyond, and an inventive method of storytelling. Abumrad has won numerous awards, including a National Headliner Award in Radio and an American Association for the Advancement of Science (AAAS) Science Journalism Award. Read his exclusive Amazon guest review of The Immortal Life of Henrietta Lacks:
Honestly, I can't imagine a better tale.
A detective story that's at once mythically large and painfully intimate.
Just the simple facts are hard to believe: that in 1951, a poor black woman named Henrietta Lacks dies of cervical cancer, but pieces of the tumor that killed her--taken without her knowledge or consent--live on, first in one lab, then in hundreds, then thousands, then in giant factories churning out polio vaccines, then aboard rocket ships launched into space. The cells from this one tumor would spawn a multi-billion dollar industry and become a foundation of modern science--leading to breakthroughs in gene mapping, cloning and fertility and helping to discover how viruses work and how cancer develops (among a million other things). All of which is to say: the science end of this story is enough to blow one's mind right out of one's face.
But what's truly remarkable about Rebecca Skloot's book is that we also get the rest of the story, the part that could have easily remained hidden had she not spent ten years unearthing it: Who was Henrietta Lacks? How did she live? How she did die? Did her family know that she'd become, in some sense, immortal, and how did that affect them? These are crucial questions, because science should never forget the people who gave it life. And so, what unfolds is not only a reporting tour de force but also a very entertaining account of Henrietta, her ancestors, her cells and the scientists who grew them.
The book ultimately channels its journey of discovery though Henrietta's youngest daughter, Deborah, who never knew her mother, and who dreamt of one day being a scientist.
As Deborah Lacks and Skloot search for answers, we're bounced effortlessly from the tiny tobacco-farming Virginia hamlet of Henrietta's childhood to modern-day Baltimore, where Henrietta's family remains. Along the way, a series of unforgettable juxtapositions: cell culturing bumps into faith healings, cutting edge medicine collides with the dark truth that Henrietta's family can't afford the health insurance to care for diseases their mother's cells have helped to cure.
Rebecca Skloot tells the story with great sensitivity, urgency and, in the end, damn fine writing. I highly recommend this book. --Jad Abumrad
Look Inside The Immortal Life of Henrietta Lacks
Click on thumbnails for larger images
Henrietta and David Lacks, circa 1945.
Elsie Lacks, Henrietta’s older daughter, about five years before she was committed to Crownsville State Hospital, with a diagnosis of “idiocy.”
Deborah Lacks at about age four.
The home-house where Henrietta was raised, a four-room log cabin in Clover, Virginia, that once served as slave quarters. (1999)
Main Street in downtown Clover, Virginia, where Henrietta was raised, circa 1930s.
Margaret Gey and Minnie, a lab technician, in the Gey lab at Hopkins, circa 1951.
Deborah with her children, LaTonya and Alfred, and her second husband, James Pullum, in the mid-1980s.
In 2001, Deborah developed a severe case of hives after learning upsetting new information about her mother and sister.
Deborah and her cousin Gary Lacks standing in front of drying tobacco, 2001.
The Lacks family in 2009.
Product Description Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.
Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.
Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.
Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.
Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?
Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
Fascinating research on researchMarch 13, 2010 S. Abeyta I was engrossed by this story of medical shenanigans and the family who paid the ultimate price for such negligence.
The author's endeavor to paint an accurate portrayal of the incidents involved in culturing the Hela cells is mind boggling.The medical community seemed to have no regress concerning the Lacks' family with the exception of one or two subservient physicians who were in no position to make any changes.
Skloot's relationship with Deborah, the youngest daughter, was phenomenal. She gained her trust despite such overwhelming odds. Their friendship seemed one of mutual respect and a life long desire to uncover all the minute details regarding the exploitation of Henrietta's cells. But Skloot had to overcome years of doubt, misgivings, and distrust of anyone delving into family history.Putting it simply, Deborah was a tough nut to crack. Through her genuine warmth, compassion, and scientific knowledge, Skloot became a trusted confidant of Deborah.
The author's skill at telling this story in such a dramatic manner made me anxious to continue reading far into the night to unveil the events as they occurred.Her writing style is simple, clear, and to the point. This reads like fiction as one story line develops into the next. The emphasis is on the human interest side of this story rather than a scholarly approach. It is one of those books that you can hardly bear to put down. It was also with regret that the story came to an end.
It is hard to know that these same medical conditions exist as of right now that allowed this travesty to happen. Beware what body parts you part with and their final destination. It is rewarding in some small way for the Lacks' family to know the medical progress accomplished due to Hela cells. But some monetary remuneration along the way would have made all their lives a little easier.
You will not be disappointed with this book.
Fascinating and extraordinary, a captivating readMarch 13, 2010 Karl Sowa(Los Angeles, CA United States) This is simply an extraordinary book. I purchased it when I heard a review on NPR and was intrigued by the science and ethics part of the story - but when I read it I was even more captivated by the human side of the story. Rebecca Skloot obviously has the facts buttoned down - and this book will probably become required reading in university medical ethics classes. The "Afterword" alone is a most fascinating review of the ethics and case law involved - but reading it without the color and nuance added by the preceding chapters would be missing the point. The story of Henrietta Lacks and her family is so skillfully woven through the science that the reader emerges at the end with a deeper understanding of the issues and a new appreciation for how human emotion plays a part. This beautifully crafted book combines history, science and sociology lessons (along with some unanswered questions) wrapped in a rich and engaging storyline that is a pleasure to read.
a well of fresh water that dried up too soon.March 12, 2010 Tonitdown(Arlington, TX USA) I could not put the book down. I read most of it aloud and really got into character. I was telling everyone that this was the book to get. It was so informative and captivating. As Henrietta was going through I felt like I was right there. I could really feel the pain of Deborah and her family. Rebecca Skloot brought this truth alive with compassion and empathy. Thank you for not being too afraid to get the whole story. It was like a well of fresh water that dried up too soon.
Medicine's mistakesMarch 12, 2010 Benjamin Andrew Roper(Texas-USA) An interesting read that shows how medicine really is a science of trial and error and in this lady's case mostly error. Yet, what happened because of her own particular differences may help change the medical world.
Excellent Read!March 11, 2010 N. C.(NW Pa) This book was an excellent read. All the complicated jargon was kept to a minimum, and the medical/legal terms were fully explained. Although the book skips around in time, the story was easy to follow. I don't usually read books in one sitting, since leisure time is short, but this book was devoured in only a few hours. Skloot's first book is a real winner, and I can't wait to read her next work. Great job!
CERTAIN CONTENT THAT APPEARS ON THIS SITE COMES FROM AMAZON SERVICES LLC. THIS CONTENT IS PROVIDED ‘AS IS’ AND IS SUBJECT TO CHANGE OR REMOVAL AT ANY TIME.
